Plant regeneration from the leaf explants of enicostemma. Drug consists of dried whole plant mostly root and vegetative parts of enicostemma hyssopifolium willd. Jun 26, 2012 mamejvo enicostemma axillare raynal is a perennial herb with diversified health benefits. Extracts of quercetin have been used to treat or prevent diverse conditions including cardiovascular disease, hypercholesterolemia, rheumatic diseases, infections and cancer but have not been shown to be effective in clinical trials for any medical condition. Dose dependent hypoglycemic effect of aqueous extract of enicostemma littorale blume in alloxan induced diabetic rats. Phytochemical and pharmacognostic value of enicostemma. Click download or read online button to get food safety theory and practice book now. Stem cylindric, glabrous with a decurrent ridge below each leaf. Preliminary study on the antimicrobial activity of enicostemma. Conclusion the terpenoids were believed to contribute to various medicinal properties. In order to download, print or access these formats you must be logged in. Leaves are sessile sometimes narrowed into a petiolelike base, longer than the internodes. Haghi, ana cristina faria ribeiro, lionello pogliani, devrim balkose, francisco torrens, omari v. Free radicals and antioxidants an open access, peer.
Oct 18, 2012 among them, enicostemma littorale blume e. Enzymatic and nonenzymatic antioxidant activities of. Pharmacognostical standardization of enicostemma littorale. Pdf hypolipidaemic and antioxidant effect of enicostemma. Enicostemma littorale is a glabrous perennial herb belonging to the family. Pharmacognostical standardization of enicostemma littorale blume the antiinflammatory activity of enicostemma littorale and mollugo cerviana. Sometimes this is spelled as enicostemma littorale. Enicostema littorale is an herb found in many parts of india. Cardioprotective and antihypertensive effects of enicostemma littorale blume extract in fructosefed rats.
Muthiah gomathinayagam, plant growth regulation lab. Abstract full text download pdf xml views 986 downloads. Hepatoprotective activity of enicostemma axillare in. Mukbaniani this volume, is designed to fulfill the requirements of scientists and engineers who wish to be. Stem cell therapy is one of the upcoming therapies for the treatment of diabetes.
Pharmacognostical standardization of enicostemma littorale blume. The present study is an attempt to screen the potential of novel small biomolecules for their differentiating property into pancreatic islet cells using nih3t3, as representative of extra pancreatic stem cells. Enicostemma littorale blume familygentianaceae a glabrous herb commonly used as a bitter tonic and substitute for swertia chirayita roxb. Enicostemma littorale is known for its hypoglycemic activity from ancient times. The journal covers all branches of pureapplied science and technology such as physics, chemistry, life sciences, medicine, earth sciences, engineering and technology. Laboratory manual in biochemistry, wiley eastern ltd, new delhi 1981, p. Methods chloroform, methanol and acetone extracts of different parts of e. Hepatomodulatory role of enicostemma littorale blume. Journal of biologically active products from nature. Kadavinaya in local language, is a perennial herb of gentianaceae family.
Methods six groups of rats were treated with ethanolic 70%vv extracts of e. Preliminary study on the antimicrobial activity of. Pdf investigation of pharmacognostical and preliminary. Enicostemma littoraleblume, adrenaline, antihypertensive activity. Download applied chemistry and chemical engineering, volume 5. The anti inflammatory activity of enicostemma littorale e. Abstract objective to study the antimicrobial activity of enicostemma littorale e.
The hepatomodulatory response of ethanol extract of enicostemma littorale blume was examined in contrast to oxidative stressinduced liver injury by carbon tetrachloride ccl4 in albino wistar male rats. Locally it is known as chota chirayita and used in indigenous medicines in the treatment of fevers and as. Evaluation of effect of aqueous extract of enicostemma. Theory and practice in hospitality and tourism research includes 111 contributions from the 2nd international hospitality and tourism conference 2014 penang, malaysia, 24 september 2014, and covers a comprehensive. A small molecule swertisin from enicostemma littorale. An effective method for isolation of pure swertiamarin from enicostemma littorale blume satyender kumar1, vinod jairaj 2 1 department of natural products, national institute of pharmaceutical education and research nip er ahmedabad opposite air force station, palaj, gandhinagar, gujarat 382354, india. The plant parts like leaves and roots are used since ages in various parts of india for treating diabetes. The present study investigates the effect of oral administration of an aqueous enicostemma littorale whole plant extract on some key carbohydrate metabolic enzymes and antioxidant defence in alloxaninduced diabetes in rats. Previously, we have reported that aqueous extract of enicostemma littorale has potential antidiabetic activity. Pdf phyto, physicochemical standardization of medicinal. Pdf phyto, physicochemical standardization of medicinal plant. Conclusion the terpenoids were believed to contribute to.
Mukbaniani this volume, is designed to fulfill the requirements of scientists and engineers who wish to be able to carry out experimental research in. Mar 14, 2010 diabetic nephropathy dn is one of the foremost causes of renal failure and a primary cause of diabetes mellitus related death. In developing countries, the majority of people rely on traditional medicines. Comparative phytochemical screening and antiarthritic potential in different extracts of enicostemma littorale and withania somnifera, proceedings and abstracts of international conference on multidisciplinary approaches icma 2014, university of sri jeyewardanepura, nugegoda, sri lanka, august 2014, p. Effect of aqueous enicostemma littorale blume extract on key. Discovery of potent differentiating agents is a prerequisite for increasing islet mass. The free radicals and antioxidants journal aims to foster the dissemination of scientific information by publishing manuscripts.
To study detailed pharmacognostic profile and preliminary phytochemical investigation of whole plant of enicostemma littorale gentianaceae is a perennial herb found throughout india. An effective method for isolation of pure swertiamarin. Plant regeneration from the leaf explants of enicostemma littorale blume through direct organogenesis. Gynoecial ontogeny in enicostemma littorale blume springerlink. The young carpel exhibits initial abaxial overgrowth followed by. Disk diffusion method was used for antimicrobial activity and bioautography was carried out for the. Keywords enicostemma littorale type 1 diabetes nephropathy stz swertiamarin r. Hypolipidaemic and antioxidant effect of enicostemma. Apr 25, 2018 enicostemma littorale blume, also known as mamajjaka in sanskrit, indian gentian in english and a. Enicostemma littorale blume scientific monograph core. The gynoecial development inenicostemma littorale blume gentianaceae has been studied. It is found distributed throughout the greater part of india and common in coastal areas. Current science is a fortnightly journal published since 1932 by the current science association, bangalore india in collaboration with the indian academy of sciences.
The free radicals and antioxidants journal aims to foster the dissemination of scientific information by publishing manuscripts that provide new insights into the biology of. Niraj mukundray bhatt, suparna barua and sarita gupta. Protective effect of enicostemma littorale blume on rat model of diabetic neuropathy. Mar 22, 2019 the main objective of this study is to evaluate the antihypertrophic potential of the aqueous extract of enicostemma littorale e. The method consisted of a simple step gradient from 10 to 20% ethyl acetate in n. Dr mrs sri ranjani sivapalan unit of siddha medicine. Swertiamarin 50 and 75 mgkg and atorvastatin 50 mgkg was given orally daily for seven consecutive day to the high cholesterol feed. Enicostemma littorale, biochemical compounds, antibacterial activity. The bittery natured plant goes about as a purgative, helps in curing fever, ailment, skin ailments, stomach issue, wind nibble, weight and controls glucose levels. This site is like a library, use search box in the widget to get ebook that you want.
Download fulltext pdf download fulltext pdf hypolipidaemic and antioxidant effect of enicostemma littorale blume article pdf available in asian pacific journal of tropical biomedicine 15. Hence the confirmation on presence of terpenoids and its antimicrobial activity shall drive the research towards determining the cytotoxic effects of the e. Enicostemma littorale blume on adrenaline induced hypertensive rats. Chhota chirayta enicostemma littorale ban labs pvt ltd. This herb is also found in south america and some parts of africa. Effect of aqueous enicostemma littorale blume extract on key carbohydrate metabolic enzymes, lipid peroxides and antioxidants in alloxaninduced diabetic rats. Enicostema littorale is an herb from the plant family gentianaceae. Abstract objective to evaluate the possible antifertility activity of enicostemma axillare e.
Hence, in our search for herbal remedies for diseases that require chronic treatment, we found that enicostemma littorale blume a glorious perennial herb. The effect of enicostemma littoraleblume on adrenalineinduced. Enicostemma littorale blume belonging to family gentianaceae. Docking analysis was carried out for the above targets with already reported phytocompounds of enicostemma axillare syn. Enicostemma littorale prevents tumor formation in 7,12.
In the present study, we have investigated the effect of aqueous extract of e. A rapid method for the isolation of swertiamarin from. It is traditionally used as antidiabetic, urinary astringent, antiperiodic, anthelmintic, anti. Traditional medicine uses cultural knowledge and practices to promote health maintenance as well as diagnose and treat disease. In vitro anti plasmodial activity of enicostemma littorale semantic. Nutritional composition and method for increasing creatine. The bicarpellary, syncarpous gynoecium begins its development in an apocarpous fashion. Volume 617, issues, 1 september 2009, pages 108112. Enicostemma littorale methanol extract in alloxaninduced diabetic rats. In the present study an attempt has been made to develop a hptlc method for quantitative estimation of swetiamarin in plants and different marketed antidiabetic polyherbal formulations. The free carpels of the young gynoecium remain open and resemble those ofmichelia champaca, polyalthia longifolia andcananga odorata studied earlier. Oral cancer is one of the most common malignancies worldwide, and india has recorded the highest annual incidence of oral cancer in comparison with other countries. Antiulcer and antiinflammatory activity of aerial parts enicostemma.
Research methodologies in modern chemistry and applied science by a. Effect of enicostemma littorale aqueous extract on serum cholesterol and triglyceride levels in cholesterol fed rats at 6th week. The content of a pharmacognosy course pdf free download. Pdf applied chemistry and chemical engineering, volume 5. Enicostemma littorale gentianaceae is also known from traditional knowledge. The rats received the extract, orally at the doses of 125, 250 and 500 mgkg b wtday for 21 consecutive days and ccl4, at the dose of 0. The whole plant is used in traditional medicine for the treatment of. Estimation of hepatic hmgco a reductase activity showed a significantly decreased activity in enicostemma littorale treated hypercholesterolemic rats.
The plant was identified and authenticated by prof. Phytochemical and pharmacognostic value of enicostemma littorale. Analysis of organic solvent extracts of enicostemma. Nasal myiasis caused by cochliomyia hominivorax in the united states. It was found to be affected by a witches broom disease under the field conditions at anand, gujarat, india. Flower size was reduced significantly in the affected plants compared.
Food safety theory and practice download ebook pdf, epub. The antiinflammatory activity of enicostemma littorale and mollugo cerviana. The aim of this study was to investigate the effect of enicostemma littorale gentianaceae aerial part on antioxidant defense systems of plasma and liver in p dimethylaminoazobenzene p dabinduced hepatocarcinoma in rats. Glucose lowering effect of aqueous extract of enicostemma. The antiinflammatory activity of enicostemma littorale and mollugo.
Erythrocentaurin is a relatively simple natural product present among the members of gentianaceae. Protective effect of enicostemma littorale blume methanolic extract on gentamicininduced nephrotoxicity in rats. A rapid and reproducible protocol has been developed for in vitro regeneration of plantlets from leaf explants of enicostemma littorale blume gentianeceae. Rapid preparative isolation of erythrocentaurin from. Pdf enicostemma littorale, blume gentianaceae is a glabrous perennial herb and it is found in open, sandy places among sparse. Amelioration of stzinduced type 1 diabetic nephropathy by.
However, lack of understanding of mechanism precludes the use of the herb and its molecules. A rapid method for the isolation of swertiamarin from enicostemma littorale. Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. Evaluation of antihypertrophic potential of enicostemma. Quercetin is a flavonoid found in many foods and herbs and is a regular component of a normal diet. Download fulltext pdf download fulltext pdf phyto, physicochemical standardization of medicinal plant enicostemma littorale, blume article pdf available march 20 with 1,618 reads. Cardioprotective and antihypertensive effects of enicostemma.
A hptlc method for quantitative estimation of swetiamarin. A hptlc method for quantitative estimation of swetiamarin in. The bittery natured plant acts as a laxative, helps in curing fever, rheumatism, skin diseases, abdominal disorders, snake bite, obesity and helps to regulate blood sugar levels. Pharmacognostic characterization of enicostemma littorale blume. Effect of aqueous enicostemma littorale blume extract on. American journal of infectious diseases science publications. We have investigated the hypolipidemic effects of swertiamarin an active lead isolated from a perennial herb enicostemma littorale blume. Morphological, anatomical and molecular investigation into. Enicostemma littorale blume is a small herb and recently we have reported its blood glucose lowering potential in alloxan induced diabetic rats.